University of Kentucky College of Agriculture, Food & Environment

 

Gluck Center > Directory > Gluck Faculty > Chambers, TM

photo of Dr. ChambersThomas M. Chambers, PhD

Gluck Equine Research Center
Department of Veterinary Science
University of Kentucky
Lexington, KY 40546-0099

E-mail: tmcham1@uky.edu
Phone: (859) 218-1126-office; 218-1173-lab
Fax: (859) 257-8542

Curriculum Vitae | Projects

Influenza is the leading cause of acute infectious respiratory disease in horses worldwide, and outbreaks occur in Kentucky annually. My laboratory is an International Reference Laboratory for equine influenza, the only one in the western hemisphere, under the auspices of the Office International des Epizooties (OIE). Thus my laboratory is called upon as one of very few centers of expertise in international surveillance for this disease. I am a member of the international Expert Surveillance Panel which meets annually to review the status of equine influenza worldwide and make recommendations to vaccine manufacturers for updating their equine influenza vaccines.

On-line presentation (pdf):
Equine influenza—recent developments

I have established three broad areas of research on equine influenza virus by my laboratory:

1. Surveillance and molecular characterization of virus strains currently in circulation, and analyses of vaccine efficacy;
2. Host-virus interaction, host immunity, and cellular-molecular pathogenesis;
3. Research towards development of more efficacious equine influenza virus vaccines

The efforts of my laboratory and my students have resulted in highly significant contributions to our field, including the development and USDA licensure of FluAvert™ (Heska Corporation, now sold by Intervet Inc.) the first intranasal, modified-live virus vaccine for equine influenza, which I have proudly described as the first equine flu vaccine in the USA that really works; and the impact of our research on maternal antibody interference upon foal vaccination schedules recommended by the American Association of Equine Practitioners. Our research on techniques for rapid diagnosis has been of considerable significance to the horse industry, e.g. in affecting import/quarantine regulations.

 

Maxwell H.Gluck Equine Research Center
Department of Veterinary Science, University of Kentucky
Lexington, Kentucky 40546-0099

Main Office (859) 257-4757
Fax (859) 257-8542