University of Kentucky College of Agriculture, Food & Environment


Gluck Center > Directory > Gluck Faculty >Chambers, TM > Curriculum Vitae


Thomas M. Chambers, Ph.D.
(859) 218-1126

Associate Professor
Department of Veterinary Science
M.H. Gluck Equine Research Center
College of Agriculture, Food & Environment
University of Kentucky

Academic Degrees

B.S. 1975; University of Notre Dame, Notre Dame, Indiana (Pre-professional Studies, with High Honors)

Ph.D. 1982; University of Notre Dame, Notre Dame, Indiana (Microbiology)

Professional Appointments

1982-85; Postdoctoral Fellow under D.P. Nayak, Department of Microbiology and Immunology, UCLA School of Medicine

1985-90; Research Associate under R.G. Webster and Assistant Member, Department of Virology and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee

1990-96; Assistant Professor, Department of Veterinary Science, University of Kentucky

1996-present; Associate Professor, Department of Veterinary Science, University of Kentucky

Head of Office International des Epizooties (OIE) Reference Laboratory for Equine Influenza, 1993-present. This is one of three such laboratories in the world, and the only one in the western hemisphere.

Co-inventor of a new equine influenza vaccine (Flu-Avert™ I.N., Heska Corporation) now at market in the USA.

Author or co-author of over 50 journal articles and book chapters, including the chapter, Equine Influenza, in the Textbook of Influenza (A. Hay and R. Webster, eds, Blackwell Scientific Press, 1998), as well as the book, Virology—A Laboratory Manual (Academic Press, 1992).

Invited speaker at over 40 national and international scientific or veterinary meetings. Participant at the 2nd and 3rd WHO/OIE Consultations on Equine Influenza, 1992 and 1995, and co-organizer of the 4th in 1999. Session chair at the 8th International Conference on Equine Infectious Diseases (Dubai 1998). Workshop Chair and member of the Local Committee for the 2002 annual meeting of the American Society for Virology.

Director of Graduate Studies, Department of Veterinary Science, 1999-2005. Lecturer or faculty participant in several graduate/undergraduate virology courses, and undergraduate advisor in Agricultural Biotechnology BS major program. Major Professor of 3 PhD and 4 MS past recipients and currently of 1 PhD and 1 MS graduate students.

Co-chair since 2002 of the University of Kentucky’s Institutional Biosafety Committee.

Recent Publications

Lai, A.C.K., Chambers, T.M., Holland, R.E. Jr., Morley, P.S., Haines, D.M., Townsend, H.G., and Barrandeguy, M.: Diverged evolution of recent equine-2 influenza (H3N8) viruses in the Western Hemisphere. Arch. Virol. 146,1063-74, 2001.

Lin, C., Zimmer, S.G., Lu, Z., Holland, R.E. Jr., Dong, Q., and Chambers, T.M.: The involvement of a stress-activated pathway in equine influenza virus mediated apoptosis. Virology 287, 202-213, 2001. (The cover illustration for the issue was from our paper.)

Lin, C., Holland, R.E. Jr., Williams, N.M., and Chambers, T.M.: Cultures of equine respiratory epithelial cells and organ explants as tools for the study of equine influenza virus infection. Arch. Virol. 146, 2239-2247, 2001.

Chambers, T.M., Holland, R.E., Tudor, L.R., Townsend, H.G., Cook, A., Bogdan, J., Lunn, D.P., Hussey, S., Whitaker-Dowling, P., Youngner, J.S., Sebring, R.W., Penner, S.J., and Stiegler, G.L.: A new modified-live equine influenza virus vaccine: Phenotypic stability, restricted spread, and efficacy against heterologous virus challenge. Equine Vet. J. 33, 630-636, 2001.

Townsend, H.G.G., Penner, S.J., Watts, T.C., Cook, A., Bogdan, J., Haines, D.M., Griffin, S., Chambers, T., Holland, R.E., Whitaker-Dowling, P., Youngner, J.S., Sebring, R.W.: Efficacy of a modified-live, temperature sensitive, intra-nasal vaccine against equine influenza: Challenge trials. Equine Vet. J. 33, 637-643, 2001.

Chambers, T.M., Lai, A.C.K., Powell, D.G., and Shortridge, K.F.: Equine influenza in China, including Hong Kong, 1989-1994. A review. Emergence and Control of Zoonotic Ortho- and Paramyxovirus Diseases, John Libbey Eurotext, Montrougue (France), pp. 55-64, 2001.

Lin, C.B., Holland, R.E. Jr., Donofrio, J.C., Tudor, L.R., and Chambers, T.M.: Caspase activation in equine influenza induced apoptotic cell death. Vet. Microbiol. 84, 357-365, 2002.

Lai, A.C.K., Rogers, K.M., Glaser, A., Tudor, L., and Chambers, T.M. Alternate circulation of recent equine-2 influenza viruses (H3N8) from two distinct lineages in the United States. Virus Research 100, 159-164, 2004.

Quinlivan, M., Zamarin, D., Garcia-Sastre, A., Cullinane, A., Chambers, T., and Palese, P.: Attenuation of equine influenza viruses through truncations of the NS1 protein. J. Virol. 79, 8431-8439, 2005.


Maxwell H.Gluck Equine Research Center
Department of Veterinary Science, University of Kentucky
Lexington, Kentucky 40546-0099

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