University of Kentucky College of Agriculture, Food & Environment

 

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CURRICULUM VITAE

Teri Lear, PhD
equigene@uky.edu
(859) 218-1108

Associate Research Professor
Department of Veterinary Science
M.H. Gluck Equine Research Center
College of Agriculture, Food & Environment
University of Kentucky

Education

1997; University of Kentucky, Department of Veterinary Science, Ph.D. (Genetics).

1986; University of Louisville, Department of Biology, M.S. (Cytogenetics/Zoology).

1975; Indiana University Southeast, Department of Natural Sciences, B.A. (Zoology/Field Biology).

Academic Positions

2005-present; Research Associate Professor, Molecular Cytogenetics, Department of Veterinary Science, University of Kentucky

1998-2005; Research Assistant Professor, Molecular Cytogenetics, Department of Veterinary Science, University of Kentucky.

Selected Publications

Holl H, Lear T, Nolen-Walston R, Slack J, Brooks S (2013).  Detection of two equine trsomies using SNP-CGH.  Mammalian Genome, 23:252-256.

Lear TL, McGee RB (2012).  Disorders of sexual development in the domestic horse, Equus caballus:  a review.  Sexual Development, 6:61-71.

Villagómez DAF, Lear TL, Chenier T, McGee R, Lee S, Cahill J, Foster RA, Reyes E, St John E, King WA (2011).  Equine disorders of sex development; XX SRY-negative, XY SRY-negative and XY SRY-positive genotypes in mares.  Sexual Development 15:16-25.

Wade CM, Guilotto E, Sigurdsson S, Zoli M, Gnerre S, Imsland F, Lear TL, et al. (2009).  Genome sequence, comparative analysis and population genetics of the domestic horse.  Science, 6 Nov, 326:865-869.

Lear TL, Bailey E (2008).  Equine clinical cytogenetics: The past and future.  Cytogenetic and Genome Research, 120:42-49.

Lear TL, Lundquist J, Zent WW, Fishback WD Jr, Clark A (2008). Three autosomal chromosome translocations associated with repeated early embryonic loss (REEL) in the domestic horse (Equus caballus).  Cytogenetic and Genome Research, 120:117-122.

Brooks S, Lear TL, Adelson D, Bailey E (2007). A chromosome inversion near the KIT gene and tobiano spotting pattern in horses.  Cytogenetic and Genome Research, 119:225-230.

Ward TL, Valberg SJ, Lear TL, Guerin G, Milenkovic D, Swinburne J, Binns MM, Chowhary BP, Raudsepp T, Skow L, Mickelson JR (2003).  Genetic mapping of GBE1 and its association with glycogen storage disease IV in American Quarter horses.  Cytogenetics and Genome Research 102:201-206.

Myka JL, Lear TL, Houck ML, Ryder OA, Bailey E (2003).  Homologous fission event(s) implicated for chromosomal polymorphisms among 5 species in the genus Equus.  Cytogenetic and Genome Research 201:217-221.

Milenkovic D, Oustry-Vaiman A, Lear TL, Billault A, Mariat D, Piumi F, Schibler L, Cribiu E, Guerin G (2002). Cytogenetic localization of 136 genes in the horse: comparative mapping with the human genome.  Mammalian Genome 13:524-534.

Lear TL, Layton G (2002).  Use of Zoo-FISH to characterize a reciprocal translocation in a Thoroughbred mare: t(1;16)(q16;q21.3).  Equine Veterinary Journal 43:207-209.

Lear TL, Brandon R, Piumi F, Terry RR, Guerin G, Thomas S, Bailey E (2001). Mapping of 31 horse genes in BACs by FISH.  Chromosome Research 9: 261-262.

Lear TL, Cox JH, Kennedy GA (1999).  Autosomal Trisomy in a Thoroughbred Colt:  65,XY,+31. Equine Veterinary Journal 31: 85-88.

Book Chapters

Lear TL.  Cytogenetics.  In:  Equine Reproductive Procedures.  Dascanio JJ and McCue PM (eds), Wiley-Balckwell, Hoboken, NJ, in press.

Lear TL, Villagomez D.  Chapter 207, The Mare: Techniques in Reproductive Examination - Cytogenetic Evaluation of Mares and Foals.  In: Equine Reproduction, second edition, 2011. Pages 1951-1962. McKinnon AO, Squires EL, Vaala WE and Varner DD (eds), Wiley-Blackwell, Chichester, UK. 

Lear TL (2006).  Cytogenetic Evaluation.  In:  Current Therapy in Equine Reproduction. JC Samper, JF Pycock, AO McKinnon (eds), Elsevier Science, St. Louis. (2006).

Selected Abstracts

Sparling AE, Coleman S, MacLeod JN, Ryder O, Bailey E, Lear TL.  Genes “unique” to equids.  Proceeding of the International Plant & Animal Genome XXI Conference, San Diego, CA, January  2013.

Lear TL, Lundquist J, Fronczek JA, Charter SJ, Little TV.  Trisomy-associated hydrops fetalis in a horse fetus.  Proceedings of the 42nd Bienninal American Cytogenetics Conference, San Antonio, TX, April 2012. Cytogenetic and Genome Research (2012) 136.4:#64.

Lear TL, Holl H, Brooks S. Detection of a 1MB chromosome deletion in horses using SNP-CGH: A potential cause of choanal atresia.  Proceedings of the 9th Dorothy Russell Havemeyer Foundation International Equine Genome Mapping Workshop, Chaska, MN, July 2011.

Lear TL, Raudsepp T, Lundquist J, Brown S. A chromosome translocation [64,XX,t(2:13)] in a Thoroughbred mare with repeated early embryonic loss.  Proceedings of the Equine Science Society Symposium, Murphreesboro, TN.  Journal of Equine Veterinary Science 31:240 (2011).

McGee RB, Lear TL, Graves KT, Bailey E (2010).  XY sex reversal in mares.  Plant & Animal Genome XVIII, San Diego, CA.

Lear TL, McGee R, Mains C, Bailey E (2009).  Characterization of SRY deletions in female horses with a 64,XY karyotype.  Proceedings of the American Society of Human Genetics, Honolulu Hawaii, November.

Lear TL (2009).  Assessing chromosome abnormalities in horses with infertility or congenital abnormalities.  Proceedings of the Equine Science Society Conference, May, Keystone CO.  Journal of Equine Veterinary Science 29: 316-317.

Villagomez DAF, Lear TL, Chenier T, Lee S, Cahill J, King WA (2008).  Equine XY and XX sex-reversal syndrome in Sry positive and negative mares.  Proceedings of the 18th International Colloquium on Animal Cytogenetics and Gene Mapping, June, Bucharest, Romania.  Chromosome Research, 16:1040.

Lear TL, Lundquist J (2008).  Chromosomal aberration associated with congenital abnormalities, infertility and repeated early embryonic loss in the domestic horse (Equus caballus). Proceedings of the 40th Biennial American Cytogenetics Conference, April 10-13, Monterey, CA.  Cytogenetic and Genome Research, 121:78-107.

Lear TL (2005).  Using horse gene mapping tools to study chromosome evolution in Perissodactyls.  Plant & Animal Genome Conference XIII, San Diego, CA.

Lear TL, Houck ML, Lundquist JM, Fronczek JA, Ryder OA (2005).  Comparative gene mapping of endangered rhinoceros species.  Plant & Animal Genome XIII, San Diego, CA.

Lear TL, Houck ML, Ryder OA (2003).  Comparative cytogenetics and gene mapping in Rhinoceroses.  13th North American Colloquium on Animal Cytogenetics and Gene Mapping, Louisville, KY.

Popular Press

Lear, TL (August 2011).  Congenital flexural limb deformities in foals. Bluegrass Equine Digest.  http://www.thehorse.com/ViewArticle.aspx?ID=18727

Bailey E, Lear TL (2009).  Closing in on the cause of swayback.  American Saddlebred, The American Saddlebred Horse Association. 

Lear TL (April 2009).  Early embryonic loss and genetics.  Equine Disease Quarterly. 

Lear TL (Oct 2008).  Contracted foal syndrome.  Equine Disease Quarterly.

Lear TL (August 2006).  The Horse Genome Project:  what does it mean? American Saddlebred, The American Saddlebred Horse Association.

Lear TL (Jan, 2001).  “Chromosomal abnormalities in horses”, Equine Disease Quarterly.

Lear TL (April, 2000).  “Equine Genome Project”, Equine Disease Quarterly.

 

Maxwell H.Gluck Equine Research Center
Department of Veterinary Science, University of Kentucky
Lexington, Kentucky 40546-0099

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