University of Kentucky College of Agriculture, Food & Environment


Gluck Center > Research > Gluck Equine Research Center > Pharmacology, Therapeutics, and Toxicology

Research - Pharmacology, Therapeutics, and Toxicology

Pain Threshold AssessmentDrugs, medications, and toxins affect horses in specific ways.  Performance altering drugs, stimulants, depressants, narcotics, and tranquilizers can all influence racing performance; the program develops highly sensitive tests for these substances.  Examples include the development of ELISA tests for narcotics and other drugs abused in horses.

Therapeutic medications protect the health and welfare of horses; the program defines regulatory concentrations and withdrawal times to enable safe use of therapeutic medication in horses in training.  Examples include defined regulatory concentrations for local anesthetics.

Therapeutic medications such as antibiotics selectively poison pathogenic microorganisms in horses; the program develops new and improved therapies for equine infectious diseases, including a unique new treatment for Equine Protozoal Myelitis (EPM).

Toxins are substances that poison horses; the program identifies substances causing toxic syndromes and develops prevention and treatment techniques for toxicoses.  Examples include work on tests for fescue toxicoses and a unique proposed pathogenesis for the Mare Reproductive Loss Syndrome (MRLS).

Pharmacology, Therapeutics, and Toxicology Faculty

Thomas Tobin


Maxwell H.Gluck Equine Research Center
Department of Veterinary Science, University of Kentucky
Lexington, Kentucky 40546-0099

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