University of Kentucky College of Agriculture

Arthur G. Hunt



Directions to University of Kentucky, Lexington, KYUniversity of Kentucky, PSS
Campus LocationPlant Science Building
1405 Veterans Drive (Office:301A)
Lexington, KY 40546-0312
Phone(859) 218-0776
Fax(859) 257-7125


Molecular biology - RNA processing and polyadenylation

1982 Ph.D., Biochemistry, Brandeis University1976 B.S., Biological Sciences, University of Lowell

1996 - Present Professor, Department of Agronomy (now Plant and Soil Sciences), University of Kentucky

1990 - 1996 Associate Professor, Department of Agronomy, University of Kentucky

1985 - 1990 Assistant Professor, Department of Agronomy, University of Kentucky

1982 - 1985 Postdoctoral Scientist, The Rockefeller University

My Site



This person page last updated on 2011-07-19


    Pls620 - Plant Molecular Biology; Credits - 3
    This course is intended to be a treatment of current concepts of plant molecular biology. It will be a literature-based course, supplemented by handouts and reading lists. The course will deal as much as is possible with topics that are unique to plants. Current aspects of molecular biology that are relevant to the course content will be covered in the first part of the course; however, these lectures will not be a review of topics that should have been retained from introductory genetics and biochemistry courses. Also, they will not be a substitute for a molecular biology course. Prereq: One semester of undergraduate genetics and biochemistry or consent of instructor. (Same as BIO 620.) .
    Instructors: Arthur G. Hunt

Research/Teaching Publications

    Books and Book Chapters

    Addepalli B., and A.G. Hunt. 2012. Diverse Roles of CCCH Zinc Finger Proteins in Stress and Plant Development Responses. In Zinc Fingers: Structure, Properties and Applications. R. Ciofani and Makrlik, eds. Nova Science Publishers. ISBN: 978-1-62100-310-6.
    Addepalli, B., Hunt, A.G. 2008. Ribonuclease activity is a common property of Arabidopsis CCCH-containing zinc-finger proteins. FEBS Letters 582, 2577-2582 Publication URL
    Arthur G.Hunt, Balasubrahmanyam Addepalli, 2008. A Polyadenylation Factor Subunit Implicated in Regulating Oxidative Signaling in Arabidopsis thaliana. PLoS One 3, e2410. Publication URL
    Hunt, A. G. 2008. Messenger RNA 3 End Formation in Plants. in Nuclear pre-mRNA Processing in Plants, Current Topics in Microbiology and Immunology 326 (M. Golovokin and ASN Reddy, eds., Springer-Verlag Berlin Heidelberg 2008), pp 151-177.
    Hunt, A. G. 2008. Messenger RNA 3 End Formation in Plants.In Nuclear pre-mRNA Processing in Plants. Chapter 9, pp. 151-177. IN: M. Golovkin and A. S. N. Reddy, eds. Current Topics in Microbiology and Immunology, vol. 326. Springer-Verlag Berlin Heidelberg.
    Hunt, A.G. 2007. Messenger RNA 3-end formation and the regulation of gene expression. Chapter 4, pp. 101-122. IN: C.L. Bassett, ed. Regulation of Gene Expression in Plants: The Role of Transcript Structure and Processing. Springer, New York.
    Wang, W., Gaffney, B., Hunt, A.G., and Tang, G. 2007. microRNAs and Plant Development. Encyclopedia of Life Sciences Publication URL
    Authors in PSS Dept.: Arthur G. Hunt Guiliang Tang

    Refereed Journal Articles

    Ma, L., P.K. Pati, M. Liu, Q.Q. Li, and A.G. Hunt. 2013. High throughput characterizations of poly(A) site choice in plants. Methods 2013:S1046-2023(13)00249-1. Published online: doi:10.1016/j.ymeth.2013.06.037.
    Hunt, A.G. 2012. RNA regulatory elements and polyadenylation in plants. Frontiers in Plant Science 2: 109.
    Hunt, A.G., D. Xing, and Q. Q. Li. 2012. Plant polyadenylation factors: conservation and variety in the polyadenylation complex in plants. BMC Genomics (13): 641.
    Thomas, P. E., X. Wu, M. Liu, B. Gaffney, G. Ji, Q. Q. Li, and A. G. Hunt*. 2012. Genome-wide control of polyadenylation site choice by CPSF30 in Arabidopsis. Plant Cell 24: 4376-4388.
    Wu, X., M. Liu, B. Downie, C. Liang, G. Ji, Q.Q. Li, and A.G. Hunt. 2011. The genome-wide landscape of polyadenylation in Arabidopsis provides evidence for extensive alternative polyadenylation. Proceedings of the National Academy of Sciences of the United States of America 108:12533-12538.
    Addepalli, B., P.A. Limbach, and A.G. Hunt. 2010. A disulfide linkage in a CCCH zinc finger motif of an Arabidopsis CPSF30 ortholog. FEBS Letters 584:4408-4412.
    Bell, S., and A.G. Hunt. 2010. The Arabidopsis ortholog of the 77 kD subunit of the polyadenylation Cleavage Stimulatory Factor is an RNA binding protein. FEBS Letters 584:1449-1454.
    Meeks, L.R., B. Addepalli, and A.G. Hunt. 2009. Characterization of genes encoding poly(A) polymerases in plants: Evidence for duplication and functional specialization. PLoS One 4, e8082. Published online: doi:10.1371/journal.pone.0008082.
    Rao, S., R.D. Dinkins, and A.G. Hunt. 2009. Distinctive interactions of the Arabidopsis homolog of the 30 kD subunit of the cleavage and polyadenylation specificity factor (AtCPSF30) with other polyadenylation factor subunits. BMC Cell Biology 10:51. Published online: doi:10.1186/1471-2164-9-220.
    Authors in PSS Dept.: Arthur G. Hunt Randy Dinkins
    Addepalli, B,, Hunt, A. G. 2008. Redox and heavy metal effects on the biochemical activities of an Arabidopsis polyadenylation factor subunit. Archives of Biochemistry and Biophysics 473, 88-95. Publication URL
    Addepalli, B., A. G. Hunt 2008. The interaction between two Arabidopsis polyadenylation factor subunits involves an evolutionarily-conserved motif and has implications for the assembly and function of the polyadenylation complex. Protein and Peptide Letters 15: 76-88.
    Arthur G.Hunt, 2008. Messenger RNA 3 end formation in plants in nuclear pre-mRNA processing in plants. Chapter 9, pp. 151-177. IN: M. Golovkin and A.S.N. Reddy, ed. Current Topics in Microbiology and Immunology, Volume 326. Springer-Verlag, Berlin/Heidelberg.
    Balasubrahmanyam, Addepalli, Arthur G.Hunt 2008. Nuclease activity is a common characteristic of Arabidopsis CCCH-containing zinc finger proteins. FEBS Letters 582:2577-2582.
    Hunt, A. G., Xu, R., Addepalli, B., Rao, S., Forbes, K. P., Meeks, L. R., Xing, D., Mo, M., Zhao, H., Bandyopadhya, A., Dampanaboina, L., Marion, A., Von Lanken, C., Li, Q. Q. 2008. Arabidopsis mRNA polyadenylation machinery: comprehensive analysis of protein-protein interactions and gene expression profiling. BMC Genomics 9, 220. Publication URL
    Authors in PSS Dept.: Arthur G. Hunt Carol Von_Lanken
    Zhang, J., B. Addepalli, K.-Y. Yun, A.G. Hunt, S. Rao, R. Xu, Q.Q. Li, and D.L. Falcone. 2008. Differential RNA processing implicated in responses of Arabidopsis thaliana to oxidative stress: A stress-tolerant mutant is deficient in a calmodulin-regulated RNA-binding protein. PloS ONE 3:e2410.
    Addepalli, B., Arthur G. Hunt. 2007. A novel endonuclease activity associated with the Arabidopsis ortholog of the 30-kDa subunit of cleavage and polyadenylation specificity factor. Nucleic Acids Research 35, 4453-4463. Publication URL
    Wang, W.-X., B. Gaffney, A.G. Hunt, and G. Tang. 2007. MicroRNAs (miRNAs) and plant development. Encyclopedia of Life Sciences, John Wiley & Sons Ltd. Published online: doi: 10.1002/9780470015902. a0020106.
    Authors in PSS Dept.: Arthur G. Hunt Guiliang Tang
    Addepalli, B., R. Xu, T. Dattaroy, B. Li, W. T. Bass, Q. Q. Li, A. G. Hunt . 2006. Disease resistance in plants that carry a feedback-regulated yeast poly(A) binding protein gene. Plant Molecular Biology 61, 383-397. Publication URL
    Delaney, K. J., R. Xu, J. Zhang, Q. Q. Li, K.-Y. Yun, D. F. Falcone, A. G. Hunt. 2006. Calmodulin interacts with and regulates the RNA-binding activity of an Arabidopsis polyadenylation factor subunit. Plant Physiology 140, 1507-1521 Publication URL
    Forbes, K. P., B. Addepalli, A. G. Hunt. 2006. An Arabidopsis Fip1 homologue interacts with RNA and provides conceptual links with a number of other polyadenylation factor subunits. Journal of Biological Chemistry 281, 176-186. Publication URL
    Addepalli, B., L.R. Meeks, K.P. Forbes, and A.G. Hunt. 2004. Novel alternative splicing of mRNAs encoding poly(A) polymerases in Arabidopsis. Biochimica Biophysica Acta 1679:117-128.